Lovenox May Be also Safe in Pediatrics Population

The safety and efficacy of use of low-molecular-weight heparin in pediatric neurosurgical patients

David D. Gonda, MD, Jared Fridley, MD, Sheila L. Ryan, MPH, JD, et al. (Journal of Neurosurgery)
The conclusions reached in the article are stated too definitively. Although this study provides new insight to the use of LMWH with this patient population, it lacks the validity of a blinded randomized controlled study comparing the effects of LMWH with the current standard of care to make claims that LMWH is safe, effective, and recommended for routine use. While their findings are encouraging, the study is too limited to confidently change patient management. At best, they’ve shown similar outcomes to treatment with unfractionated heparin or oral anticoagulants, which may provoke further research on the topic.

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